One of the most frequent clinical decisions during an IVF cycle is choosing between a Fresh Embryo Transfer (performed 3-5 days after retrieval) or a Frozen Embryo Transfer (FET, where embryos are vitrified and transferred in a subsequent cycle).
Advancements in flash-freezing technology (Vitrification) have transformed outcomes. Below is a comparative medical overview prepared by Dr. Vandana Mishra.
Fresh Embryo Transfer
In a fresh transfer, embryos are cultured in the lab for 3 to 5 days and placed into the uterus during the same stimulation cycle.
- Pros: Shortens overall time to first transfer attempt; no freezing fee.
- Cons: High estrogen levels from stimulation medications may occasionally reduce endometrial receptivity or increase Ovarian Hyperstimulation Syndrome (OHSS) risk in high-responder patients.
Frozen Embryo Transfer (FET)
With FET, all high-quality embryos are vitrified. The patient's body is given 1 to 2 months to rest, allowing hormone levels to return to baseline before uterine preparation.
- Pros: Mimics natural uterine environment; significantly reduces OHSS risk; higher success rates in patients with elevated progesterone during stimulation; allows Preimplantation Genetic Testing (PGT).
- Cons: Requires cryopreservation phase and additional preparation cycle.
95%+ Vitrification Survival Rate
At Good News IVF Patna, our modern liquid nitrogen vitrification technology ensures over 95% embryo survival post-thaw with zero loss in cellular quality.
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